22 February, 2018
"Unfortunately, it still remains unclear which diet is the best for weight loss, and who the true demons really are ... carbs or fat", she says.
Lead study author Christopher Gardner, the director of nutrition studies at the Stanford Prevention Research Center, noted that the point of the study wasn't to compare a low-fat diet to a low-carb one to see which was best for weight loss, as many previous studies have done.
Professor Gardner recruited 609 participants between the ages of 18 and 50 for his tests. Craig Pickering of DNAFit said that genes besides the three in the Stanford study can contribute to weight loss as well as fat loss and gain, as a small 2007 study found, and that it is "putting the finishing touches" on a study showing that "subjects on a genetically matched diet lost more weight" than did those on a one-size-fits-all low-carb diet. The other group went low-fat, starting with no more than 20 grams of fat per day, the equivalent to a handful of nuts.
After that they added back five to 15 grams of fat or carbs gradually, aiming to reach a balance they believed they could maintain for the rest of their lives.
By the end of the study, the researchers found variations in the results.
At the end of the year, people on a low-fat diet reported a daily average fat intake of 57 grams while those on low-carb diets consumed about 132 grams of carbs per day.
The study participants were not told to count calories or anything, but had to limit either their fat or carbohydrate intake.
Flood watch issued into Tuesday morning
The potholes on numerous roads may also be filled with water, which also requires motorists to slow down in some areas. By Saturday , up to 6 inches of rain is forecast in several rounds of precipitation across much of the state.
Before they embarked on the study, each participant had part of their genome sequenced and their baseline insulin outputs measured.
A recent trend in healthy eating circles has been a "genotype" diet.
"We told everybody they should buy whole foods. Also, we advised them to diet in a way that didn't make them feel hungry or deprived - otherwise it's hard to maintain the diet in the long run", said Gardner.
In a 600-person, year-long study, the two eating styles helped dieters drop nearly exactly the same number of pounds - and there didn't seem to be much rhyme or reason as to who succeeded on which plan, explains study author Christopher Gardner, director of nutrition studies at the Stanford Prevention Research Center. However, some lost as much as 50-60 pounds.
Further, vast weight loss variability was observed among the participants of both the groups. Contrary to what they suspected, there were no associations between the genotype pattern or insulin levels and weight loss. His research team is "continuing to delve into their databanks, now asking if the microbiome, epigenetics or a different gene expression pattern can clue them in to why there's such drastic variability between dieting individuals", it continues.
For you the reader, the biggest takeaways would be that there isn't a clear-cut victor between low-fat and low-carb. In fact, it's an idea that's taken off in recent years, with companies promoting "DNA diets" that will help you shed pounds. "Eat less sugar, less refined flour and as many vegetables as possible".
Even though cutting calories wasn't a goal for these dieters, people might still achieve this by replacing junk food with healthier alternatives, said Kevin Hall, a researcher at the National Institute of Diabetes and Digestive and Kidney Diseases who wasn't involved in the study.
"I'm hoping that we can come up with signatures of sorts", he added.